Application of green tea extracts epigallocatechin-3-gallate in dental materials: Recent progress and perspectives.

Department of Oral Implantology, West China Hospital of Stomatology; State Key Laboratory of Oral Diseases, Sichuan University, Chengdu, Sichuan, China. Stomatology College & the Affiliated Stomatology Hospital of Southwest Medical University, Luzhou, Sichuan, China.

Journal of biomedical materials research. Part A. 2020;(12):2395-2408
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Abstract

Because of excellent biocompatibility, antioxidant activity, and anti-caries ability, epigallocatechin-3-gallate (EGCG) has been widely studied in the treatment of oral diseases, such as periodontal disease, oral cancer, and dental caries. To reach the site of the lesion or achieve sustained release, play the role of anti-caries, anti-inflammatory, or to maintain or improve the physical properties of the modified material,EGCG need to be cross-linked or embedded with dental adhesives, barrier membranes, bone replacement materials, tissue regeneration materials, and antimicrobial anti-caries materials to better prevent or treat oral diseases. This article reviews the applications of EGCG in oral materials, involving various areas of the oral cavity, reveals their excellent potential, and sees shortcomings in these research to promote the better development of EGCG applications in oral materials such as oral repair materials, bone tissue engineering materials and antibacterial and anti-caries materials.

Methodological quality

Publication Type : Review

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